The most common presentation after a benzodiazepine overdose is central nervous system depression, slurred speech, impaired balance, and lack of muscle coordination. It may occur due to accidental consumption of large amounts of the drug (acute overdose) or may be due to long-term consumption of larger quantities than recommended (chronic exposure).
Ingestion of large doses of benzodiazepines results in toxicity and adverse effects. In some cases, benzodiazepines are also used as an anesthetic agent before surgical procedures. Because of these actions, they are used for the treatment of different conditions.Ĭan Xanax cause depression, insomnia, and anxiety? The typical examples of benzodiazepines that we use are as follows.īenzodiazepine shows anticonvulsant,sedative,and calming effects.
They differ in the rate of absorption, potency, and outcomes. There are different types of benzodiazepines available for medical use. They enhance the effect of gamma-aminobutyric acid neurotransmitters (GABA) and induce hypnotic, sedative, muscle relaxant, and anti-anxiety effects. Benzodiazepines mediate their action through gamma-aminobutyric acid A receptors (GABA-A) in the central nervous system. They also contain a variable side chain that determines the drug's action duration, potency, elimination rate, and metabolic activity. What Are Benzodiazepines?īenzodiazepines are organic compounds with a benzene ring and a diazepine ring. The toxicity of benzodiazepines may cause central nervous system depression, slurred speech, lack of muscle coordination, and respiratory depression. The toxicity of benzodiazepines is aggravated when they are taken in combination with other medications (tricyclic antidepressants, opiates) and alcohol. However, toxicity and adverse health effects are observed in individuals with benzodiazepine overdose and abuse. Benzodiazepines, when taken at recommended levels, are considered safe. The widespread use and easy availability of benzodiazepine drugs have led to drug overdose and abuse. They treat conditions such as seizures, insomnia, and anxiety. Benzodiazepine drugs are a group of psychoactive drugs which alter the central nervous system functions and cause altered consciousness, mood, perception, and behavior.
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